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Borderline ovarian tumours (BOT), i.e., tumors with a potentially low level of malignancy, belong to a single category of epithelial new formations in the International Hystological Classification of WHO and make up to 8–16% Twenty-five percent of recurrences were diagnosed after five years [ 14 ], though relapses may actually occur 15 years after surgery, so patients must be closely monitored for a long time. A univariate analysis of the follow-up results and recurrence indicated that the median follow-up time of these 286 patients with borderline tumors was 54 months (9–117 months), and 40 patients had a recurrence, the recurrence rate being 13.9%, and the median recurrence time being 48 months. Borderline tumors of the ovary (also called tumors of low malignant potential) are a heterogeneous group of lesions defined histologically by atypical epithelial proliferation without stromal invasion [ 1 ]. The behavior of these tumors is distinct from low-grade ovarian carcinoma, and they are considered a … Gynecologists and obstetricians typically encounter borderline ovarian tumors in the course of managing adnexal masses. In contrast to invasive epithelial ovarian cancers, borderline tumors are more likely to occur in premenopausal women and are more likely to be stage I, … While borderline ovarian tumors generally have an excellent prognosis with a 5‑year survival of > 95%, recurrences and malignant transformation occur in a small percentage of patients. Nevertheless, the identification of patients at increased risk for recurrence remains difficult.

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Methods A retrospective review of patients with BOBT treated or referred to our institutions. A centralized histological review by a reference The recurrence of disease was higher after fertility-sparing surgery (35 of 189 cases) than after radical surgery (seven of 150 cases); nevertheless, all but one woman with recurrence of borderline tumor or progression to carcinoma after conservative surgery were salvaged. Mucinous borderline tumors produce large multicystic masses with smooth outer surfaces that may resemble benign mucinous cystadenomas. PMP is defined clinically on the basis of intraoperative findings as a grossly visible, localized, or generalized accumulation of mucus in the pelvis or abdomen, either lying on and attached to the peritoneal surfaces or incorporated within dense fibrous tissue. Serous borderline tumor of the ovary initially was described in 1929 by Taylor. 1 Current information suggests that women with Stage I serous borderline tumors have an excellent prognosis, with a disease free survival rate approaching 100%.

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Very rarely, these cells start to grow into the underlying tissue. Borderline ovarian tumors represent a heterogeneous group of noninvasive tumors of uncertain malignant potential with characteristic histology. They occur in younger women, are present at an early stage, and have a favorable prognosis, but symptomatic recurrence and death may be found as long as 20 years after therapy in some patients.

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Ovarian serous borderline tumor (SBT) is a low grade epithelial neoplasm of generally younger women with a favorable prognosis when diagnosed at an early stage Defined, nonobligate precursor to low grade serous carcinoma (LGSC) As a borderline tumor, can give rise to extra-ovarian abdominoperitoneal or lymph node implants The other patient with serous borderline tumor had recurrence in the pouch Douglas as a non-invasive implant after 6 months of initial comprehensive surgical staging for stage IIIC disease. After the initial surgery, she received 6 courses of paclitaxel + cisplatin and then was subjected to surgery for clinical recurrence. A univariate analysis of the follow-up results and recurrence indicated that the median follow-up time of these 286 patients with borderline tumors was 54 months (9–117 months), and 40 patients had a recurrence, the recurrence rate being 13.9%, and the median recurrence time being 48 months. Borderline ovarian tumor. Borderline ovarian tumours differ from epithelial ovarian cancer by their low incidence, frequent association with infertility, low association with mutations in BCRA genes, different percentages of the most common histological types, early stage diagnosis, and high survival rate, even when associated with peritoneal involvement.

The five patients diagnosed with benign tumors experienced local recurrence within a median time of approximately one year (IQR: 0.75-2 years; Figure 2).
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Eighteen pregnancies (nine spontaneous) were observed in 14 patients. CONCLUSIONS: This study demonstrates that spontaneous pregnancies can be achieved after conservative treatment of advanced-stage borderline ovarian tumors (with noninvasive implants) but the recurrence rate is high. 2012-05-14 Article.

borderline ovarian tumors as compared to early stage invasive ovarian cancer.
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Tumors of low malignant potential (i.e., borderline tumors) account for 15% of all epithelial ovarian cancers. Nearly 75% of these tumors are stage I at the time of diagnosis. These tumors must be recognized because their prognosis and treatment is clearly different from the frankly malignant invasive carcinomas. With respect to individual subgroups, 5-year outcomes for women with benign, borderline, and malignant phyllodes tumors were as follows: Local recurrence - 6%, 9%, and 21%, resectively Phyllodes tumors are a fibroepithelial tumor composed of an epithelial and a cellular stromal component.

Risk factors for local recurrence in patients with pTa/pT1

2005-09-01 · The other patient with serous borderline tumor had recurrence in the pouch Douglas as a non-invasive implant after 6 months of initial comprehensive surgical staging for stage IIIC disease.

Rapport 3 - 2014. Colorectal cancer-incidence in relation to consumption of red and processed meat by Per Ola Darnerud and Nils-Gunnar Ilbäck  Atypical / borderline changes in glandular cells. 146.